G12V (p.Gly12Val) variant of RAC1 (P63000)
G12V (p.Gly12Val) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
G12V (p.Gly12Val) variant details
- p.Gly12Val
- cosmic curated COSV61823
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.71
- CADD 33.00
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available