G12E (p.Gly12Glu) variant of RAC1 (P63000)
G12E (p.Gly12Glu) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
G12E (p.Gly12Glu) variant details
- p.Gly12Glu
- gnomAD 7-6374770-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.671
- REVEL 0.70
- CADD 33.00
- PolyPhen-2 0.66
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available