G12A (p.Gly12Ala) variant of RAC1 (P63000)
G12A (p.Gly12Ala) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
G12A (p.Gly12Ala) variant details
- p.Gly12Ala
- gnomAD 7-6374770-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.63
- REVEL 0.65
- CADD 29.10
- PolyPhen-2 0.81
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available