F28C (p.Phe28Cys) variant of RAC1 (P63000)
F28C (p.Phe28Cys) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
F28C (p.Phe28Cys) variant details
- p.Phe28Cys
- gnomAD 7-6387259-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.755
- REVEL 0.82
- CADD 29.50
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available