C6W (p.Cys6Trp) variant of RAC1 (P63000)
C6W (p.Cys6Trp) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
C6W (p.Cys6Trp) variant details
- p.Cys6Trp
- gnomAD 7-6374753-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.698
- REVEL 0.76
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available