C6S (p.Cys6Ser) variant of RAC1 (P63000)
C6S (p.Cys6Ser) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
C6S (p.Cys6Ser) variant details
- p.Cys6Ser
- gnomAD 7-6374751-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.69
- CADD 27.70
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available