A3D (p.Ala3Asp) variant of RAC1 (P63000)
A3D (p.Ala3Asp) in RAC1 (P63000) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A3D (p.Ala3Asp) variant details
- p.Ala3Asp
- gnomAD 7-6374743-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.32
- CADD 23.90
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available