T2N (p.Thr2Asn) variant of PTPRC (P08575)
T2N (p.Thr2Asn) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
T2N (p.Thr2Asn) variant details
- p.Thr2Asn
- ExAC rs768227005
- gnomAD rs768227005
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- CADD 21.50
- PolyPhen-2 0.06
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available