P41L (p.Pro41Leu) variant of PTPRC (P08575)
P41L (p.Pro41Leu) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P41L (p.Pro41Leu) variant details
- p.Pro41Leu
- gnomAD rs1471347474
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.12
- CADD 11.50
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available