M3T (p.Met3Thr) variant of PTPRC (P08575)
M3T (p.Met3Thr) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
M3T (p.Met3Thr) variant details
- p.Met3Thr
- ExAC rs772724488
- TOPMed rs772724488
- gnomAD rs772724488
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.34
- CADD 25.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available