L35S (p.Leu35Ser) variant of PTPRC (P08575)
L35S (p.Leu35Ser) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
L35S (p.Leu35Ser) variant details
- p.Leu35Ser
- ESP rs369827350
- ExAC rs369827350
- TOPMed rs369827350
- gnomAD rs369827350
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.21
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.80
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available