L10F (p.Leu10Phe) variant of PTPRC (P08575)
L10F (p.Leu10Phe) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- gnomAD rs1186725402
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.20
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available