G25V (p.Gly25Val) variant of PTPRC (P08575)
G25V (p.Gly25Val) in PTPRC (P08575) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G25V (p.Gly25Val) variant details
- p.Gly25Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.23
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.09
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available