G25E (p.Gly25Glu) variant of PTPRC (P08575)
G25E (p.Gly25Glu) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G25E (p.Gly25Glu) variant details
- p.Gly25Glu
- gnomAD rs1174394984
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.19
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available