F16L (p.Phe16Leu) variant of PTPRC (P08575)
F16L (p.Phe16Leu) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
F16L (p.Phe16Leu) variant details
- p.Phe16Leu
- gnomAD rs1662444892
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.11
- CADD 18.10
- PolyPhen-2 0.04
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available