F16I (p.Phe16Ile) variant of PTPRC (P08575)
F16I (p.Phe16Ile) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
F16I (p.Phe16Ile) variant details
- p.Phe16Ile
- gnomAD 1-198639314-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.12
- CADD 22.50
- PolyPhen-2 0.77
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available