A11T (p.Ala11Thr) variant of PTPRC (P08575)
A11T (p.Ala11Thr) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A11T (p.Ala11Thr) variant details
- p.Ala11Thr
- ExAC rs759684142
- gnomAD rs759684142
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.16
- CADD 24.20
- PolyPhen-2 0.79
- SIFT 0.09
- Most common in the East Asian population (allele frequency 7.6e-05)
- Structural context available