A11S (p.Ala11Ser) variant of PTPRC (P08575)
A11S (p.Ala11Ser) in PTPRC (P08575) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
A11S (p.Ala11Ser) variant details
- p.Ala11Ser
- ExAC rs759684142
- gnomAD rs759684142
- Missense
- Variant Prioritization Score for Impact Estimate 0.393
- REVEL 0.18
- CADD 25.90
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available