Y69C (p.Tyr69Cys) variant of PTPN4 (P29074)
Y69C (p.Tyr69Cys) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
Y69C (p.Tyr69Cys) variant details
- p.Tyr69Cys
- Ensembl rs1677777215
- Missense
- Variant Prioritization Score for Impact Estimate 0.85
- REVEL 0.96
- ESM-1b 1.00
- AlphaMissense 0.74
- MetaLR 0.82
- MetaSVM 0.90
- CADD 26.90
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available