Y13C (p.Tyr13Cys) variant of PTPN4 (P29074)
Y13C (p.Tyr13Cys) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
Y13C (p.Tyr13Cys) variant details
- p.Tyr13Cys
- gnomAD rs1488003248
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.73
- ESM-1b 1.00
- AlphaMissense 0.23
- MetaLR 0.67
- MetaSVM 0.37
- CADD 28.10
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available