V58F (p.Val58Phe) variant of PTPN4 (P29074)
V58F (p.Val58Phe) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data, published literature, and structural context.
V58F (p.Val58Phe) variant details
- p.Val58Phe
- gnomAD 2-119862569-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.886
- REVEL 0.94
- ESM-1b 1.00
- AlphaMissense 0.76
- MetaLR 0.82
- MetaSVM 0.87
- CADD 27.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available