V45L (p.Val45Leu) variant of PTPN4 (P29074)
V45L (p.Val45Leu) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
V45L (p.Val45Leu) variant details
- p.Val45Leu
- gnomAD rs1691550118
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.38
- ESM-1b 0.00
- AlphaMissense 0.18
- MetaLR 0.42
- MetaSVM -0.51
- CADD 23.40
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available