T79K (p.Thr79Lys) variant of PTPN4 (P29074)
T79K (p.Thr79Lys) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
T79K (p.Thr79Lys) variant details
- p.Thr79Lys
- gnomAD 2-119862633-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.06
- ESM-1b 0.00
- AlphaMissense 0.21
- MetaLR 0.21
- MetaSVM -0.80
- CADD 21.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available