T2P (p.Thr2Pro) variant of PTPN4 (P29074)
T2P (p.Thr2Pro) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T2P (p.Thr2Pro) variant details
- p.Thr2Pro
- TOPMed rs1390419226
- gnomAD rs1390419226
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.33
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.37
- MetaSVM -0.45
- CADD 25.10
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available