T27S (p.Thr27Ser) variant of PTPN4 (P29074)
T27S (p.Thr27Ser) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T27S (p.Thr27Ser) variant details
- p.Thr27Ser
- TOPMed rs1691549071
- gnomAD rs1691549071
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- REVEL 0.37
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.28
- MetaSVM -0.67
- CADD 22.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available