T27I (p.Thr27Ile) variant of PTPN4 (P29074)
T27I (p.Thr27Ile) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
T27I (p.Thr27Ile) variant details
- p.Thr27Ile
- TOPMed rs1691549071
- gnomAD rs1691549071
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- REVEL 0.42
- ESM-1b 1.00
- AlphaMissense 0.17
- MetaLR 0.38
- MetaSVM -0.33
- CADD 25.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available