T12A (p.Thr12Ala) variant of PTPN4 (P29074)
T12A (p.Thr12Ala) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
T12A (p.Thr12Ala) variant details
- p.Thr12Ala
- gnomAD 2-119809887-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.13
- ESM-1b 0.35
- AlphaMissense 0.11
- MetaLR 0.35
- MetaSVM -0.55
- CADD 23.30
- Population evidence available
- Structural context available
- Literature evidence available