R83T (p.Arg83Thr) variant of PTPN4 (P29074)
R83T (p.Arg83Thr) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
R83T (p.Arg83Thr) variant details
- p.Arg83Thr
- gnomAD 2-119877324-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- REVEL 0.51
- ESM-1b 1.00
- AlphaMissense 0.87
- MetaLR 0.36
- MetaSVM -0.52
- CADD 23.60
- Population evidence available
- Structural context available
- Literature evidence available