R6P (p.Arg6Pro) variant of PTPN4 (P29074)
R6P (p.Arg6Pro) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data, published literature, and structural context.
R6P (p.Arg6Pro) variant details
- p.Arg6Pro
- gnomAD 2-119809870-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.55
- ESM-1b 1.00
- AlphaMissense 0.51
- MetaLR 0.57
- MetaSVM 0.18
- CADD 34.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available