R6G (p.Arg6Gly) variant of PTPN4 (P29074)
R6G (p.Arg6Gly) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R6G (p.Arg6Gly) variant details
- p.Arg6Gly
- gnomAD rs1366276778
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.47
- ESM-1b 1.00
- AlphaMissense 0.38
- MetaLR 0.52
- MetaSVM -0.01
- CADD 27.60
- Most common in the South Asian population (allele frequency 0.00011)
- Structural context available