R24G (p.Arg24Gly) variant of PTPN4 (P29074)
R24G (p.Arg24Gly) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R24G (p.Arg24Gly) variant details
- p.Arg24Gly
- 1000Genomes rs146868631
- ESP rs146868631
- ExAC rs146868631
- TOPMed rs146868631
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- REVEL 0.40
- ESM-1b 1.00
- AlphaMissense 0.17
- MetaLR 0.37
- MetaSVM -0.13
- CADD 26.10
- Most common in the 1KG:YRI population (allele frequency 0.017)
- Structural context available