P8S (p.Pro8Ser) variant of PTPN4 (P29074)
P8S (p.Pro8Ser) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P8S (p.Pro8Ser) variant details
- p.Pro8Ser
- Ensembl rs2104948279
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.19
- ESM-1b 0.00
- AlphaMissense 0.28
- MetaLR 0.37
- MetaSVM -0.47
- CADD 28.40
- Most common in the HGDP:MANDENKA population (allele frequency 0.025)
- Structural context available