N81Y (p.Asn81Tyr) variant of PTPN4 (P29074)
N81Y (p.Asn81Tyr) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
N81Y (p.Asn81Tyr) variant details
- p.Asn81Tyr
- gnomAD 2-119862638-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.536
- REVEL 0.45
- ESM-1b 1.00
- AlphaMissense 0.12
- MetaLR 0.36
- MetaSVM -0.29
- CADD 24.70
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available