N81I (p.Asn81Ile) variant of PTPN4 (P29074)
N81I (p.Asn81Ile) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
N81I (p.Asn81Ile) variant details
- p.Asn81Ile
- gnomAD 2-119862639-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.20
- ESM-1b 0.31
- AlphaMissense 0.10
- MetaLR 0.30
- MetaSVM -0.66
- CADD 24.30
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available