N32S (p.Asn32Ser) variant of PTPN4 (P29074)
N32S (p.Asn32Ser) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
N32S (p.Asn32Ser) variant details
- p.Asn32Ser
- gnomAD 2-119809948-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.27
- ESM-1b 0.00
- AlphaMissense 0.09
- MetaLR 0.35
- MetaSVM -0.58
- CADD 21.70
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available