L74M (p.Leu74Met) variant of PTPN4 (P29074)
L74M (p.Leu74Met) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
L74M (p.Leu74Met) variant details
- p.Leu74Met
- gnomAD 2-119862617-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.47
- ESM-1b 0.00
- AlphaMissense 0.10
- MetaLR 0.49
- MetaSVM -0.10
- CADD 21.40
- Population evidence available
- Structural context available
- Literature evidence available