L72I (p.Leu72Ile) variant of PTPN4 (P29074)
L72I (p.Leu72Ile) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
L72I (p.Leu72Ile) variant details
- p.Leu72Ile
- gnomAD 2-119862611-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- REVEL 0.77
- ESM-1b 1.00
- AlphaMissense 0.21
- MetaLR 0.78
- MetaSVM 0.59
- CADD 24.20
- Population evidence available
- Structural context available
- Literature evidence available