L62V (p.Leu62Val) variant of PTPN4 (P29074)
L62V (p.Leu62Val) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
L62V (p.Leu62Val) variant details
- p.Leu62Val
- gnomAD rs1317528901
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- REVEL 0.60
- ESM-1b 1.00
- AlphaMissense 0.13
- MetaLR 0.47
- MetaSVM -0.22
- CADD 24.30
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available