L20V (p.Leu20Val) variant of PTPN4 (P29074)
L20V (p.Leu20Val) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L20V (p.Leu20Val) variant details
- p.Leu20Val
- gnomAD 2-119809911-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.16
- ESM-1b 1.00
- AlphaMissense 0.09
- MetaLR 0.35
- MetaSVM -0.41
- CADD 22.80
- Population evidence available
- Structural context available
- Literature evidence available