K44N (p.Lys44Asn) variant of PTPN4 (P29074)
K44N (p.Lys44Asn) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
K44N (p.Lys44Asn) variant details
- p.Lys44Asn
- Ensembl rs1457060082
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.31
- ESM-1b 1.00
- AlphaMissense 0.25
- MetaLR 0.34
- MetaSVM -0.53
- CADD 23.70
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available