K44E (p.Lys44Glu) variant of PTPN4 (P29074)
K44E (p.Lys44Glu) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
K44E (p.Lys44Glu) variant details
- p.Lys44Glu
- gnomAD rs1240011706
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.19
- ESM-1b 1.00
- AlphaMissense 0.14
- MetaLR 0.20
- MetaSVM -0.85
- CADD 23.10
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available