I33V (p.Ile33Val) variant of PTPN4 (P29074)
I33V (p.Ile33Val) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I33V (p.Ile33Val) variant details
- p.Ile33Val
- gnomAD rs1313332778
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.06
- MetaSVM -1.00
- CADD 12.31
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available