H61R (p.His61Arg) variant of PTPN4 (P29074)
H61R (p.His61Arg) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
H61R (p.His61Arg) variant details
- p.His61Arg
- ExAC rs757862652
- gnomAD rs757862652
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.49
- ESM-1b 1.00
- AlphaMissense 0.20
- MetaLR 0.36
- MetaSVM -0.45
- CADD 24.60
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available