F70Y (p.Phe70Tyr) variant of PTPN4 (P29074)
F70Y (p.Phe70Tyr) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
F70Y (p.Phe70Tyr) variant details
- p.Phe70Tyr
- gnomAD rs1401955462
- Missense
- Variant Prioritization Score for Impact Estimate 0.799
- REVEL 0.88
- ESM-1b 0.86
- AlphaMissense 0.68
- MetaLR 0.80
- MetaSVM 0.84
- CADD 26.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available