F43L (p.Phe43Leu) variant of PTPN4 (P29074)
F43L (p.Phe43Leu) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
F43L (p.Phe43Leu) variant details
- p.Phe43Leu
- gnomAD 2-119809982-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.49
- ESM-1b 1.00
- AlphaMissense 0.88
- MetaLR 0.40
- MetaSVM -0.42
- CADD 25.80
- Population evidence available
- Structural context available
- Literature evidence available