D80G (p.Asp80Gly) variant of PTPN4 (P29074)
D80G (p.Asp80Gly) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
D80G (p.Asp80Gly) variant details
- p.Asp80Gly
- gnomAD 2-119862636-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.548
- REVEL 0.66
- ESM-1b 0.00
- AlphaMissense 0.16
- MetaLR 0.37
- MetaSVM -0.33
- CADD 34.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available