D77N (p.Asp77Asn) variant of PTPN4 (P29074)
D77N (p.Asp77Asn) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
D77N (p.Asp77Asn) variant details
- p.Asp77Asn
- ExAC rs552737169
- gnomAD rs552737169
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.30
- ESM-1b 0.00
- AlphaMissense 0.10
- MetaLR 0.44
- MetaSVM -0.41
- CADD 27.80
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available