D77E (p.Asp77Glu) variant of PTPN4 (P29074)
D77E (p.Asp77Glu) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
D77E (p.Asp77Glu) variant details
- p.Asp77Glu
- gnomAD 2-119862628-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.29
- ESM-1b 0.00
- AlphaMissense 0.10
- MetaLR 0.34
- MetaSVM -0.56
- CADD 19.93
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available