D63N (p.Asp63Asn) variant of PTPN4 (P29074)
D63N (p.Asp63Asn) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
D63N (p.Asp63Asn) variant details
- p.Asp63Asn
- TOPMed rs1324562768
- gnomAD rs1324562768
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.22
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.17
- MetaSVM -0.84
- CADD 24.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available