D49Y (p.Asp49Tyr) variant of PTPN4 (P29074)
D49Y (p.Asp49Tyr) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
D49Y (p.Asp49Tyr) variant details
- p.Asp49Tyr
- gnomAD 2-119862542-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.562
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.23
- MetaLR 0.44
- MetaSVM -0.18
- CADD 24.60
- Population evidence available
- Structural context available
- Literature evidence available